high risk

00:00 - 04:20  Turning the tables: Bret Scher the interviewer interviewed!
04:20 - 06:48  What made Bret change course? 
06:50 - 08:17  If I'm having a heart attack I still want stents and statins!
08:20 - 14:40  Metabolic Psychiatry: What enticed Bret to move from DietDoctor to Metabolic Mind?
14:41 - 16:35  Graham's childhood experience growing up in a household surrounded  by poor  mental health
16:40 - 21:00  Defining mental health and Improving Brain Health!
21:01 - 24:44  What is Nutritional Ketosis and what are the benefits?
24:47 - 30:16  Poor mental health is a death sentence!
30:17 - 38:47  The link between poor metabolic health and poor mental health              
38:48 -  44:52  Achieving remission of mental health symptoms via nutritional ketosis
44:53- 52:14   Next Steps: Clinical Trials for Nutritional Ketosis in Mental Health   
52:20 - 58:14   Fighting the anti-Keto dogma   

00:00 - 08:55 - Introduction
08:56 - 12:55 - WEGOVY - is that the answer?  
12:20 - 14:56 - What is causing the obesity pandemic?
14:57 - 23:17 - How can we solve the pandemic of obesity and diabetes?
23:18 - 46:20 - Medication? Balancing the benefits, the harms and the Costs!
46:21 - 60:00 - The Public Health Collaboration Charity - Come to our Conference in  May!
60:01 - 69:41 - Q&A: Ask Dr Unwin!
69:42 - 71:35 - And finally...

In this episode, Renslow Sherer, MD, and Trinh P. Vu, PharmD, BCIDP, discuss strategies for managing ambulatory patients with acute or previous COVID-19 infection, including:

• Current COVID-19 landscape
• Rapid antigen tests and PCR tests
• Risk stratification of patients who have a positive SARS-CoV-2 test
• Antiviral treatment (nirmatrelvir + ritonavir, remdesivir, and molnupiravir)
• Long COVID

Presenters:
Renslow Sherer, MD
Director, International HIV Training Center
Professor of Medicine
Section of Infectious Diseases and Global Health
Department of Medicine
University of Chicago
Chicago, Illinois

Trinh P. Vu, PharmD, BCIDP
Clinical Pharmacy Specialist in Infectious Diseases
Department of Pharmaceutical Services
Emory University Hospital Midtown
Atlanta, Georgia

To download the slides: bit.ly/3oHKC09

To view the full online program: bit.ly/4201xcO

In this episode, Renslow Sherer, MD, and Trinh P. Vu, PharmD, BCIDP, discuss strategies for managing ambulatory patients with acute or previous COVID-19 infection, including:

• Current COVID-19 landscape
• Rapid antigen tests and PCR tests
• Risk stratification of patients who have a positive SARS-CoV-2 test
• Antiviral treatment (nirmatrelvir + ritonavir, remdesivir, and molnupiravir)
• Long COVID

Presenters:
Renslow Sherer, MD
Director, International HIV Training Center
Professor of Medicine
Section of Infectious Diseases and Global Health
Department of Medicine
University of Chicago
Chicago, Illinois

Trinh P. Vu, PharmD, BCIDP
Clinical Pharmacy Specialist in Infectious Diseases
Department of Pharmaceutical Services
Emory University Hospital Midtown
Atlanta, Georgia

To download the slides: bit.ly/3oHKC09

To view the full online program: bit.ly/4201xcO

In this episode, Renslow Sherer, MD, and Trinh P. Vu, PharmD, BCIDP, discuss strategies for managing ambulatory patients with acute or previous COVID-19 infection, including:

• Current COVID-19 landscape
• Rapid antigen tests and PCR tests
• Risk stratification of patients who have a positive SARS-CoV-2 test
• Antiviral treatment (nirmatrelvir + ritonavir, remdesivir, and molnupiravir)
• Long COVID

Presenters:
Renslow Sherer, MD
Director, International HIV Training Center
Professor of Medicine
Section of Infectious Diseases and Global Health
Department of Medicine
University of Chicago
Chicago, Illinois

Trinh P. Vu, PharmD, BCIDP
Clinical Pharmacy Specialist in Infectious Diseases
Department of Pharmaceutical Services
Emory University Hospital Midtown
Atlanta, Georgia

To download the slides: bit.ly/3oHKC09

To view the full online program: bit.ly/4201xcO

In this episode, Tracey Piparo, PA-C, and Renslow Sherer, MD, discuss cases of nonhospitalized patients with COVID-19, including:

• Young, healthy patient with no risk factors
• Young, healthy patient with risk factors
• Older patient with immunocompromise
• Older patient with renal dysfunction
• Patient experiencing hypoxia 

Presenters: 

Tracey Piparo, PA-C 
Department of Palliative Medicine 
RJWBarnabas 
New Brunswick, New Jersey 

Renslow Sherer, MD 
Director, International HIV Training Center 
Professor of Medicine 
Section of Infectious Diseases and Global Health 
Department of Medicine 
University of Chicago 
Chicago, Illinois 

To download the slides: bit.ly/44cgH0q

To view the full online program: https://bit.ly/4201xcO

00:00 - 04:50 - "and now for something different" meet Cory Jenks another pharmacist who gave up drugs and he's and Improv Comedian! 
04:55 - 12:36 - Are UK pharmacists and US pharmacists the same or different? 
12:42 - 15:18 - How did Cory become Low Carb and "give up drugs?" 
15:19 - 21:00 - A pharmacist who has a sense of humour?? Its good for patients !! 
21:01 - 24:32 - Medicine has lost its humanity! 
24:33 - 33:43 - Live Healthy for Longer! 
33:44 - 41:55 - How can our kids be healthy surrounded by junk food?  
41:55 - 1:02:58 - Low Carb Denver - we had a blast!  
1:03:00- 1:07:55 - What's next for Cory?

In this episode, Maria Buti, MD, and Richard H. Davis, PA-C, address key considerations when screening, diagnosing, and treating patients with hepatitis delta virus (HDV), such as:

• Barriers to screening 
• HDV screening based on patient risk factors 
• Universal screening for all patients with positive hepatitis B surface antigen (HBsAg)
• Reflex testing 
• Availability of commercial testing
• Monitoring suggestions in HBsAg positive and HDV antibody positive patients with negative HDV RNA
• Limitations to evaluating advanced fibrosis in patients with HDV
• Data on novel HDV therapies (eg, bulevirtide and lonafarnib)
• Extending HDV therapy (eg, peginterferon) based on treatment response
• Stopping rules (eg, HDV RNA negativity, HBsAg loss) for discontinuing HDV therapy

Faculty:

Maria Buti, MD
Professor of Medicine
Hospital Universitario Vall d’Hebron
Barcelona, Spain

Richard H. Davis, PA-C
Senior PA
Gastroenterology
University of Florida
UF Health
Gainesville, Florida

Link to full program: 
http://bit.ly/3yp1Lxf

Adriaan is a vastly experienced executive in Physical Security, Loss Prevention and Risk Management helping organisations become more resilient to complex threats. Around the campfire, he entertains others with accounts of adventure and adversity from a life boldly lived. With a career spanning two decades in safety and security, he lives out his passion for people by bringing together and leading teams of professionals, developing turnaround security strategies for multinational companies trading in complex environments. 

He is an independent thinker with a global perspective and a working background across four continents. Grounded by a military background and a pedigree of taking a hands-on approach he combines conventional security knowledge with real-world applications to deliver unique security risk management solutions. 

His ability to strategise, formulate and implement solutions that deliver tangible results in challenging operating environments is legendary. In 2022 he was named the 4th most influential security executive globally by IFSEC global as well as being featured in the International Security Journal special Influencers Edition of the industry’s 30 most celebrated individuals. He doesn't have a degree, he hasn't written any books and he sits on no committees, what he does have are results. If you like to get in touch you can reach out to him at www.linkedin.com/in/adriaanbosch.

Security Circle ⭕️ is an IFPOD production for IFPO the International Foundation of Protection Officers

Fernando Carnavali, MD; Rasika Karnik, MS, MD; Renslow Sherer, MD; and Joseph Torrisi, PharmD, BCIDP, discuss how to ethically prioritize patients for COVID-19 treatment when treatment supplies may be limited, including insights on:

• Risk stratification
• Medication acquisition
• Drug interactions

Presenters:

Fernando Carnavali, MD
Associate Professor of Medicine
Division Chief
General Internal Medicine
Department of Medicine
Site Director 
COVID Center of Excellence Satellite-Ansonia 
Mount Sinai Health 
New York, New York

Rasika Karnik, MS, MD
Assistant Professor
Division of Primary Care
Department of Internal Medicine
University of Chicago
Medical Director
Post-COVID Recovery Clinic
Chicago, Illinois

Renslow Sherer, MD
Director
International HIV Training Center
Professor of Medicine
Section of Infectious Diseases and Global Health
Department of Medicine
University of Chicago
Chicago, Illinois

Joseph Torrisi, PharmD, BCIDP
Clinical Pharmacy Specialist
Infectious Diseases 
Pharmacy
Grady Health System
Atlanta, Georgia

Link to slides: 
https://bit.ly/3hXMgId

Link to full program: 
https://bit.ly/3G271KL

Chapters: 

0.00 - Introduction (Ken's personal journey) 

7.00 - Lies My Doctor Told Me 

10.00 - You are what you eat 

18.00 - Big Food and Big Pharma are killing us slowly 

23.17 - Make your doctor think! 30.23 - Is cholesterol really the problem? 

34.20 - Is eating less and moving more the way to weight loss? 

40.07 - A species-appropriate diet for homo sapiens 

45.24 - What does Ken eat? 

54.30 - All calories are not  equal 

1:00:00 - The profound link between your diet and your mental health 

1:00:17 - Sunlight isn’t bad for you after all 

1:10:00 - Conclusion 

Join Ken Berry's private group discussed in this podcast: https://phdhealth.community/ 

Learn more about Ken Berry here: https://drberry.com/about/

Chapters

00:00 - 09:43 Introduction
10:10 - 12:20 Michael's portfolio career the GP extraordinaire:  "I work too much"
12:20 - 17:09 Continuity of Care is SO important for patients
17:10 - 23:51 Why Michael started BodyMapping Clinic - providing specialist blood tests.
23:52 - 27:15 In the NHS - we treat secondary symptoms not primary root causes
27:18 - 30:15 Testing, testing, testing ... so  what? 
30:15 - 36:30 How BodyMapping works for ProLongevity clients
36:32 - 49:15 Michael reviews Graham's BodyMapping test results
49:16 - 56:41 Explaining the balance sheet of your health 
56:50 - 61:30 Graham's lipids (cholesterol) are not good. Should he take a statin? 
61:30 - 67:35 Supplements - can they make a difference?  
67:40 - 72:20 Longevity: Living longer in good health. How metabolic age is measured? Can ageing be slowed down or reversed?  (Pheno-age)

Chapters:

00:00 - 01:06  Introduction
01:07 - 12:15 Dr. Tro's Personal Journey (No longer a 250lb Family Physician!)
12:16 - 13:04 Why Tro created The Society of Metabolic Health Practitioners              
                      { https://thesmhp.org/about-us/mission/ } 
13:05 - 18:13 Perverse Incentives (How do US and UK Health Care Systems compare?)
18:18 - 23:34 Changing the Treatment Paradigm (Once you've tried it you can't go  back!) 
23:35 - 24:10 The LowCarbMD podcast - had over 6 million downloads
                      { https://www.lowcarbmd.com/ }
24:11 -  32:08 Why the Healthcare System works neither for patients NOR health  professionals "I just want a Doctor who is going to listen!"
32:10 - 43:14 How Big Food and Big Pharma have rigged the system for profit
43:15 - 46:50 "Empowerment" Tro's treatment paradigm!
46:51 -  55:31 Escaping the "Tyranny of Food!"
55:33 - 01:01:05 Next Steps: Tro's Health Research from Case Series to Published Papers
                       { https://www.mdpi.com/2218-1989/12/9/848 } 
01:05:41 - 01:14:08 Should we worry about LDL? (so-called "bad" cholesterol) 
01:14:10 - 01:17:05  In Conclusion!   

In this podcast, Gary S. Marshall, MD, summarizes the burden of meningococcal disease and the importance of immunization, including: 

• The unpredictability and severity of meningococcal disease
• Differences between meningococcal serogroups and available vaccines 
• Current meningococcal vaccine recommendations, distinguishing between routine vs shared clinical decision-making recommendations 
• Vaccine recommendations in high-risk populations 
• Use of immunization platforms to help complete age-appropriate vaccines, including the MenACWY and MenB vaccine, in adolescents and young adults

Faculty:

Gary S. Marshall, MD
Professor of Pediatrics
Division of Pediatric Infectious Diseases
University of Louisville School of Medicine
Louisville, Kentucky

Link to full program:
https://bit.ly/3T0GLG2

Chris revisits the key points made by Jack Jarvis, adds his own insights and gives listeners some suggestions for practical actions they can take immediately to help them get where they want to go.

The book explains Perrow’s theory that catastrophic accidents are inevitable in tightly coupled and complex systems. His theory predicts that failures will occur in multiple and unforeseen ways that are virtually impossible to predict. 

Charles B. Perrow (1925 – 2019) was an emeritus professor of sociology at Yale University and visiting professor at Stanford University. He authored several books and many articles on organizations and their impact on society. One of his most cited works is Complex Organizations: A Critical Essay, first published in 1972.

Discussion Points:

• David and Drew reminisce about the podcast and achieving 100 episodes
• Outsiders from sociology, management, and engineering entered the field in the 70s and 80s
• Perrow was not a safety scientist, as he positioned himself against the academic establishment
• Perrow’s strong bias against nuclear power weakens his writing
• The 1979 near-disaster at Three Mile Island - Perrow was asked to write a report, which became the book, “Normal Accidents…”
• The main tenets of Perrow’s core arguments:
• Start with a ‘complex high-risk technology’ - aircraft, nuclear, etc
• Two or more values start the accident
• “Interactive Complexity”
• 787 Boeing failures - failed system + unexpected operator response lead to disaster
• There will always be separate individual failures, but can we predict or prevent the ‘perfect storm’ of mulitple failures at once?
• Better technology is not the answer
• Perrow predicted complex high-risk technology to be a major part of future accidents
• Perrow believed nuclear power/nuclear weapons should be abandoned - risks outweigh benefits
• Three reasons people may see his theories as wrong:
• If you believe the risk assessments of nuclear are correct, then my theories are wrong
• If they are contrary to public opinion and values
• If safety requires more safe and error-free organizations
• If there is a safer way to run the systems outside all of the above
• The modern takeaway is a tradeoff between adding more controls, and increased complexity
• The hierarchy of designers vs operators
• We don’t think nearly enough about the role of power- who decides vs. who actually takes the risks?
• There should be incentives to reduce complexity of systems and the uncertainty it creates
• To answer this show’s question - not entirely, and we are constantly asking why 

Quotes:

“Perrow definitely wouldn’t consider himself a safety scientist, because he deliberately positioned himself against the academic establishment in safety.” - Drew

“For an author whom I agree with an awful lot about, I absolutely HATE the way all of his writing is colored by…a bias against nuclear power.” - Drew

[Perrow] has got a real skepticism of technological power.” - Drew

"Small failures abound in big systems.” - David

“So technology is both potentially a risk control, and a hazard itself, in [Perrow’s] simple language.” - David

Resources:

The Book – Normal accidents: Living with high-risk technologies

The Safety of Work Podcast

The Safety of Work on LinkedIn

Feedback@safetyofwork

Chapters:

00:00 - Intro

01:51 - Warren’s story

13:17 - “Life Begins at 65”

17:14 - Warren’s diet

21:10 - XtendLife

40:10 - Final thoughts

Winners Never Quit (ft. Jack Jarvis)

Jack Jarvis on how challenges become opportunities

OPENING QUOTE:

“If I hadn’t been unsuccessful on UKSF selection, I never would've been here, wouldn't have done what I did when I rode across the Atlantic, raised £70,000 for charity. So everything happens for a reason.”

—Jack Jarvis

GUEST BIO:

Jack Jarvis left school at just 16 to join the army as a soldier in the Royal Engineers, the military engineering part of the British Army, which enables mobility of action and denies the same to the enemy. Jack's determination and his belief in giving 100% by the age of 20 saw him successfully passing the extremely tough British military commando course and leading seven other soldiers in dynamic high risk environments. He then went on to become the first person to row solo across the Atlantic from mainland Europe to the mainland United States.

CORE TOPICS + DETAILS:

[16:08] - Competence and Leadership

Two traits for essential leaders

Jack reflects on how all the great leaders he’s respected over the years have done two things. They’ve committed themselves to being leaders by example, never asking someone to do something they wouldn’t do themselves. And they also are committed to growing their competency. If they don’t have an answer, they’ll go and get it. We should all strive to be this kind of dependable leader. 

[21:26] - The Bulletproof Mindset

Failure isn’t something to be ashamed of

Jack recounts his greatest life failure, and how it became the impetus for his greatest success. It made him realize that he had what he calls a “bulletproof mindset,” the ability to simply never quit and never be ashamed of failing. He’s since channeled that mindset into everything he does today.

[29:31] - Work Your Way Up to Incredible

A journey of smaller challenges

Did Jack immediately wake up and decide to row for 111 days across a dangerous ocean? No. In Chris’ words, “You can't just go straight to the biggest challenge of your life, because what happens is you need to go on a journey of smaller challenges that build you up and build you up and build you up. You have to go through the failures, which then become your learning points.”

[32:51] - Showing Initiative with Your Ideas

Jack’s advice for attracting investors and supporters

Jack didn’t have a concrete product or a guaranteed investment return. What he had was ideas, and he accepted his need to be tenacious with those ideas and never stop going hard at every opportunity he could find. That’s how he got the support he needed from some of the world’s most influential organizations.

RESOURCES:

• [1:17] About the Corps of Royal Engineers
• [2:54] About Jack’s Solo Atlantic Crossing

Follow Jack Jarvis:

• LinkedIn

Follow Chris Roebuck:

• Website
• Twitter
• LinkedIn
• Facebook
• Perspectives from the Top

ABOUT PERSPECTIVES FROM THE TOP:

Discover the secrets of success for you and your organization shared by the world’s leading thinkers, doers, and trailblazers. Join Chris Roebuck, Honorary Visiting Professor of transformational leadership, leader in military, business, and government, inspiring global keynote speaker, one of HR’s Most Influential Thinkers, bestselling author, and your host of Perspectives from the Top. The show reveals a treasure trove of insights from mega trends to practical strategies and actions to take your career up a gear. From government world shapers and business mold breakers to evidence driven academics and enthusiastic entrepreneurs, each episode shows you how you can immediately use these new ideas and actions to drive your success.

Learn more at: PerspectivesFromTheTop.com

ABOUT DETROIT PODCAST STUDIOS:

In Detroit, history was made when Barry Gordy opened Motown Records back in 1960. More than just discovering great talent, Gordy built a systematic approach to launching superstars. His rigorous processes, technology, and development methods were the secret sauce behind legendary acts such as The Supremes, Stevie Wonder, Marvin Gaye, Diana Ross and Michael Jackson.

As a nod to the past, Detroit Podcast Studios leverages modern versions of Motown’s processes to launch today’s most compelling podcasts. What Motown was to musical artists, Detroit Podcast Studios is to podcast artists today. With over 75 combined years of experience in content development, audio production, music scoring, storytelling, and digital marketing, Detroit Podcast Studios provides full-service development, training, and production capabilities to take podcasts from messy ideas to finely tuned hits. 

Here’s to making (podcast) history together.

Learn more at: DetroitPodcastStudios.com

ABOUT THE HOST:

Chris has shown over 21,000 leaders in over 1500 organizations globally how they can discover their secrets of success in a way that meets and beats their organizations specific challenges.

Chris has done this across sector, culture and geography - UBS, HSBC, KPMG & London Underground, legal firms to construction, tech and IT, to retail, facilities to scientific research, police to not for profit, pharmaceutical to SMEs. From the UK National Health Service of 1.4m staff and UK Government to the Red Cross in Myanmar, from Investment banks in London to Middle East Telecoms, from the Chinese Space Program leaders to HR Directors in India and global retail CEOs in Rome.

When he was the Global Head of Leadership at UBS, overseeing a staff of 70,000 across 100 countries, his team helped the bank transform organizational performance to increase profitability by 235%, market capitalization by 50% and win numerous awards. This is now a Harvard Case Study.

Chris has been quoted as a business leadership expert globally in the Harvard Business Review China, FT, Wall Street Journal, Le Monde, New York Times, Business Week, Time Magazine, Washington Post, Times of India, Straits & Gulf Times and many others. He judges business awards and has done over 350 TV interviews on leadership and business on BBC, Sky, Bloomberg, Al Jazeera, CNBC & CNN. He’s also skied at 60mph by accident. 

Learn more about Chris at: ChrisRoebuck.Live

CREDITS:

• Chris Roebuck: Host | chris@chrisroebuck.net 
• Connor Trombley: Executive Producer | connor@detroitpodcaststudios.com