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    #153 - AMA #21: Deep dive into olive oil, high-intensity exercise, book update, and more

    enMarch 15, 2021

    Podcast Summary

    • Exploring the World of Authentic Olive OilLearn about the importance of extra virgin olive oil, how to identify its authenticity, and the differences between various types of oils. Understand the impact of taste and smell, and the role of vegetable oils and saturated fats in a healthy diet.

      The importance of understanding the quality and authenticity of olive oil. Bob the Cap Kaplan and I delve deep into the topic, discussing what makes olive oil extra virgin, the differences between various types of oils, and how to ensure you're getting the real deal. We also touch on related topics like vegetable oils, saturated fats, and the importance of taste and smell in evaluating olive oil. Additionally, we answer some quick questions on training zones, massage tools, standing desks, and more. So, whether you're a seasoned olive oil connoisseur or just starting your health and wellness journey, this episode has something for you. To learn more about our membership benefits and access the full Ask Me Anything episode, visit PeterAtiaMD.com forward slash subscribe.

    • Observational data links olive oil to heart health benefitsOlive oil's cardio-protective properties stem from observational data of Mediterranean diet, but the full picture involves understanding fatty acids and dietary patterns.

      The perceived health benefits of olive oil, particularly its cardio-protective properties, stem primarily from the observational data of the Mediterranean diet. Ansel Keys, who is known for his work in measuring serum blood cholesterol in the 1950s, observed that societies that consumed large amounts of olive oil as part of their diet had lower rates of heart disease. However, it's important to note that this is just the tip of the iceberg when it comes to understanding the health benefits of olive oil and the role of fatty acids in our diet. The conversation also touched upon the idea of dipping cigarettes in olive oil, which was quickly dismissed, and the possibility of infusing olive oil with other substances. Overall, the discussion highlighted the complexity of understanding the health benefits of olive oil and the importance of considering the broader context of fatty acids and dietary patterns.

    • Ancel Keys' Research on Cholesterol and Heart DiseaseAncel Keys' initial research linked high cholesterol levels to heart disease, leading to the belief that diet could influence cholesterol and heart health. Later research revealed that not all fats are equal, with monounsaturated fats being cardio-protective.

      Ancel Keys' research in the 1950s showed a correlation between total cholesterol levels and heart disease. He discovered that people with the lowest and highest total cholesterol levels had significantly different rates of heart disease. This observation led to the belief that diet could influence cholesterol levels, with saturated fats being a particular concern due to their link to higher cholesterol levels and heart disease. However, as research progressed, it became clear that not all types of fat were equal, and monounsaturated fats were found to be cardio-protective. By the 1970s, Keys shifted his focus to the benefits of monounsaturated fats over saturated fats in preventing heart disease.

    • Understanding Different Types of Dietary Fats: Saturated, Monounsaturated, and PolyunsaturatedSaturated fats are solid at room temperature and linked to heart disease, while monounsaturated and polyunsaturated fats are liquid, important for heart health, and help lower bad cholesterol

      Understanding the different types of dietary fats - saturated, monounsaturated, and polyunsaturated - is essential for making informed food choices. Saturated fats, such as palmitic acid, have single bonds between their carbon atoms and are fully saturated with hydrogen. Monounsaturated fats, like oleic acid, have one double bond and are less saturated with hydrogen. Polyunsaturated fats, such as linoleic acid, have multiple double bonds and are even less saturated with hydrogen. This difference in hydrogen saturation affects the physical properties and health effects of each type of fat. Saturated fats tend to be solid at room temperature and have been linked to increased cholesterol levels and heart disease. Monounsaturated and polyunsaturated fats are liquid at room temperature and are important for heart health, as they help to lower bad cholesterol and raise good cholesterol. By knowing the difference between these types of fats, we can make more informed decisions about the foods we eat and promote better health. This discussion also touched upon the idea that the MOFA olive oil story began around 50 years ago.

    • Understanding the impact of double bonds on fat classificationSaturated fats have no double bonds, monounsaturated fats have one, and their properties depend on the location of the double bond.

      While all fats consist of long chains of carbon atoms, the number and placement of double bonds within those chains significantly impact their properties and classification. Saturated fats, such as palmitic and stearic acids, have no double bonds and are denoted with two numbers, indicating the number of carbons and the absence of double bonds. For example, palmitic acid is 16:0, and stearic acid is 18:0. Monounsaturated fats, on the other hand, have one double bond, and their nomenclature includes an additional piece of information: the location of the double bond. For instance, oleic acid is 18:1, and the "N" indicates the ninth carbon, where the double bond is located. The side from which counting starts is also important, as the same numbering can refer to different carbons depending on the side. Thus, two monounsaturated fats of the same length can have different properties based on the location of their double bonds. Understanding the nomenclature and the impact of the number and placement of double bonds is crucial for comprehending the properties and health effects of various fats.

    • Join The Drive podcast for exclusive benefitsMembers receive comprehensive show notes, private podcast feed, discounts, and ongoing benefits, enhancing their learning experience without relying on ads.

      The discussion touched upon the benefits of becoming a member of The Drive podcast, which includes access to comprehensive show notes, a private podcast feed with additional content, steep discounts on recommended products, and ongoing benefits. The membership program aims to provide in-depth content without relying on paid ads. To learn more and access these member-only benefits, visit peteratiamd.com/subscribe. Members can also download the member-only podcast feed at peteratiamd.com/members. The podcast itself is for general informational purposes only and does not constitute medical advice. If you're already a member, make sure you have downloaded the member-only podcast feed. You can find the host, Peter Atia MD, on various social media platforms and leave a review on your preferred podcast player.

    • Importance of seeking professional medical adviceAlways consult healthcare professionals for medical conditions and avoid relying solely on podcasts or self-diagnosis.

      While listening to this podcast can provide valuable information, it should not replace professional medical advice. The content discussed in the podcast is not a substitute for a proper diagnosis or treatment from a healthcare professional. It's essential to consult with healthcare experts for any medical conditions you may have. Additionally, the speaker takes conflicts of interest seriously and encourages listeners to check out his website, peteratiamd.com/about, for a comprehensive list of companies he has investments or advisory roles in. Always prioritize your health and safety by seeking professional help when needed.

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    View the Show Notes Page for This Episode

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    View the Show Notes Page for This Episode

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    View the Show Notes Page for This Episode

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    • Parting thoughts and takeaways [1:27:00]; and
    • More.

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    The Peter Attia Drive
    enMay 13, 2024

    #300 - Special episode: Peter on exercise, fasting, nutrition, stem cells, geroprotective drugs, and more — promising interventions or just noise?

    #300 - Special episode: Peter on exercise, fasting, nutrition, stem cells, geroprotective drugs, and more — promising interventions or just noise?

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    In this special edition celebrating 300 episodes of The Drive, Peter discusses a variety of popular topics and health interventions and classifies them based on their level of evidence and relevance using the following categories: proven, promising, fuzzy, noise, and nonsense. Peter first delves into the topic of geroprotective molecules, covering rapamycin, metformin, NAD and its precursors, and resveratrol. Next, he explores the significance of metrics like VO2 max and muscle mass, as well as emerging concepts like blood flow restriction and stem cells. The conversation extends to nutrition, addressing questions surrounding long-term fasting, sugar consumption, sugar substitutes, and the contentious role of red meat in cancer. Peter not only provides his current stance on each topic—most of which have been covered in great detail in the previous 300 episodes—but also reflects on how his opinion may have evolved over the years.

    We discuss:

    • Defining the categories of “proven, promising, fuzzy, noise, and nonsense” [3:15];
    • Rapamycin [9:30];
    • Metformin [17:00];
    • NAD and its precursors [24:30];
    • Resveratrol [32:45];
    • The importance of VO2 max, muscle mass, and muscular strength for lifespan [38:15];
    • Blood flow restriction (BFR) training [44:00];
    • Using stem cells to treat osteoarthritis or injury [51:30];
    • Fasting as a tool for longevity (and why Peter stopped his fasting protocol) [55:45];
    • The energy balance theory [1:06:30];
    • The idea that sugar is poison [1:12:00];
    • The idea that sugar substitutes are dangerous [1:22:15];
    • The debate on red meat and cancer [1:28:45]; and
    • More.

    Connect With Peter on TwitterInstagramFacebook and YouTube

    Special episode with Dax Shepard: F1 and the 30th anniversary of Ayrton Senna’s death

    Special episode with Dax Shepard: F1 and the 30th anniversary of Ayrton Senna’s death

    View the Show Notes Page for This Episode

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    This is a special episode of The Drive with Peter’s friend and fellow car enthusiast Dax Shepard. In this podcast, which commemorates the 30th anniversary of the death of Brazilian Formula One legend Ayrton Senna, Dax sits down with Peter to better understand what made Senna so special and why Peter remains an enormous fan. This conversation focuses on Senna’s life, the circumstances of his death, and his lasting impact and legacy on the sport of F1.

    We discuss:

    • Peter’s interest in motorsports began as a child [2:30];
    • The drama and dangers of F1 [6:00];
    • What made Senna special [13:00];
    • What Senna meant to Brazilians [24:00];
    • The cause of the fatal crash [28:15];
    • Why Peter is obsessed with Senna [40:30];
    • Being the best versus having the best record [43:30];
    • Senna’s unique driving style and incredible intuition about automotive engineering [46:30];
    • Back to the day of the dreadful race [53:00];
    • What Peter believes caused the crash [1:02:45];
    • Views on dying young, in the prime of life [1:13:00];
    • Senna lives on in his foundation and in safety changes adopted by F1 [1:21:00];
    • Statistics aren’t enough for fandom, and why people like who they do [1:24:15];
    • The biggest difference between F1 today and F1 in the 80s [1:28:30];
    • Senna’s driving superpower [1:30:30];
    • The fastest drivers currently in F1 [1:38:30];
    • Current F1 obsessions [1:45:00];
    • How hard it is to do what the top F1 drivers do [1:50:15];
    • Dax’s love of motorcycles and his AMG E63 station wagon [1:52:15];
    • Awesome Senna mementos from Etsy [2:01:15];
    • What makes specialists interesting, and Max’s devotion to F1 [2:10:15];
    • What Senna might have done if he had not died that day [2:14:00];
    • Michael Schumacher and Max Verstappen are also top F1 drivers [2:17:30];
    • Interlagos in Sao Paulo Brazil is always an incredible experience [2:18:45]; and
    • More.

    Connect With Peter on TwitterInstagramFacebook and YouTube

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