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    • Brain, genetics, and society's role in gender dysphoriaGender dysphoria results from a combination of biological, genetic, and social factors. Brain areas like BST may influence gender identity, while societal expectations and early childhood experiences can contribute to feelings of gender dysphoria.

      Gender dysphoria, a mismatch between a person's biological sex and their felt gender, can be explained through a combination of biological, genetic, and social factors. The brain sex theory suggests that certain areas of the brain, such as the bed nucleus of the stria terminalis (BST), may contribute to gender identity and can vary in size based on an individual's identified gender rather than their biological sex. Studies have suggested that genetic factors may play a role in some cases of gender dysphoria, but social factors also play a significant role. For instance, societal expectations and the pressure to conform to gender norms can contribute to feelings of gender dysphoria and confusion. Additionally, the psychoanalytic theory suggests that early childhood experiences, such as separation anxiety and overly close mother-son relationships, may contribute to the development of gender dysphoria in some individuals. However, it's important to note that assumptions about brain sex have been challenged, and further research is needed to fully understand the complex interplay of biological, genetic, and social factors in the development of gender dysphoria.

    • New study suggests hormone therapy may impact brain structure in transgender individualsTransgender individuals' brain structures may align with their identified gender before hormone therapy, challenging the notion that hormones cause gender dysphoria. Societal influences and the recognition of non-binary genders also contribute to understanding gender identity.

      The differences in the brain structure of transgender individuals, specifically in the Bed nucleus of the stria terminalis (BST), may be a result of hormone therapy rather than the cause of gender dysphoria. Before hormone treatment, the distribution of white matter in the brains of transgender individuals more closely resembled their identified gender than their biological sex. This finding suggests that there may be early differences in the brains of transgender individuals. Additionally, the recognition of more than two genders in various cultures and the increasing number of people identifying as non-binary indicates that gender identity and dysphoria are socially constructed rather than biological facts. However, it's important to note that the psychoanalytic theory, specifically Obssian Person's theory and Recker's theory from 1986, do not provide a comprehensive account of gender dysphoria, particularly in the case of transgender females. Therefore, a more nuanced understanding of gender dysphoria is necessary, incorporating both biological and social factors.

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