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    EP. 126: Anti-Aging + Immune Centric Approach to Health | Joel Greene

    enJanuary 24, 2024

    Podcast Summary

    • Learning from Joel Green about an immune-centric approach to healthJoel Green highlights the importance of an immune-centric approach to health, weight loss, and anti-aging. Sodium butyrate, a supplement that influences GLP-1 production, can aid in immune function and overall health. Alatorra Naturals offers natural, organic skin care products to support overall wellness.

      Learning from this episode of the Doctor Tina Show is the importance of an immune-centric approach to health, anti-aging, and weight loss. Joel Green, a renowned biohacker and author of "The Immunity Code," emphasized that when the immune system goes into a pro-inflammatory state, it can lead to various health issues. Sodium butyrate, a supplement that impacts the hormone GLP-1 by altering the behavior of certain cells in our gut, can help turn on our own natural endogenous production of GLP-1. Additionally, taking care of our skin is crucial for overall health, and Alatorra Naturals offers a line of handcrafted natural skin care products that are all natural, cruelty-free, nontoxic, non-GMO, and organic when possible. The use of code "doctorTina20" at checkout on bodybio.com and alitura.com can save listeners 20% on their orders of sodium butyrate and Alatorra Naturals products, respectively.

    • A personal journey to question conventional fitness adviceThrough a personal experience of gaining weight despite following fitness advice, the speaker discovered the importance of continually questioning and adapting to new information in the health and wellness field.

      Despite dedicating three decades to following fitness advice from industry experts, the speaker found himself gaining weight in the early 2000s. This experience led him to question the effectiveness of conventional wisdom and sparked a new focus on longevity and food usage. He created a nutrition software in 2008, which incorporated research on the gut microbiome, and spent years gathering data through corporate wellness programs. Despite the challenges and financial ups and downs, he eventually wrote "The Immunity Code" in 2016, which gained popularity after being featured on Ben Greenfield's podcast. This journey underscores the importance of continually questioning and adapting to new information in the ever-evolving field of health and wellness.

    • Understanding the context of dietary approachesDr. Baker's 'The Immunity Code' introduced many health trends, but 'The Way' provides a clearer framework for diet decisions based on context.

      The book "The Immunity Code" by Dr. Shawn Baker has had a significant impact on modern health and wellness trends, introducing concepts like mouth taping, cold plunging, and high-intensity workouts. The book, which launched in 2018, popularized many ideas that are now common on social media. However, Dr. Baker recognized that the book left some areas unaddressed, particularly regarding diet. This led him to write a new book, "The Way," to provide a clearer framework for understanding diet and making decisions based on one's own sense. The importance of considering the context of when certain dietary approaches are effective is a key concept from "The Immunity Code" that has remained relevant. While the book may be complex for some, its comprehensive and scientific approach resonated with Dr. Baker, who is an academic and scientist at heart. The discussion also touched on the potential downsides of focusing too much on one trend or piece of information at a time, as seen on social media.

    • Four fundamental forces impacting diet and lifestyle choicesLong-term diet and lifestyle choices can have different effects at various stages. Four fundamental forces - accumulation, defense, attenuation, and compensation - influence how the body responds to these choices.

      The effectiveness of a diet or lifestyle choice can change over time. The body responds differently to the same input at different stages. According to the speaker, there are four fundamental forces at play: accumulation, defense, attenuation, and compensation. Over time, something will accumulate, degrade, attenuate, and compensate in response to any given protocol. For instance, long-term high protein, low carb diets can induce insulin resistance and lead to a compensation in the colon, making it a cancer-promoting environment. Similarly, the kidneys degrade over time, and high protein intakes can accelerate this process. The speaker also mentions the importance of understanding that time matters and that the same diet or lifestyle choice that works well at one point in time may be detrimental at another.

    • Insulin and Adiponectin: Complex Interactions Affecting Nutrition and HealthInsulin and Adiponectin, two hormones crucial for blood sugar regulation and insulin sensitivity, have complex interactions influenced by age, organ function, and gut bacteria. Older adults may face unique challenges due to decreased adiponectin secretion and changes in the vasculature.

      When it comes to nutrition and health, there is no one-size-fits-all answer. Insulin, a hormone that plays a crucial role in regulating blood sugar levels, doesn't work in isolation. It is part of a family of hormones, and its effectiveness is influenced by various factors such as age, organ function, and the specific bacteria in the gut. Adiponectin, another hormone secreted by body fat, is essential for insulin sensitivity and has been linked to numerous age-related diseases. Saturated fats, a common dietary concern, can be particularly challenging for older adults due to decreased adiponectin secretion and changes in the vasculature over time. Understanding these complex interconnections can help us make more informed choices about our diet and overall health.

    • Aging leads to excess free radicals and inflammation in the vasculatureAs we age, imbalance between NOx enzymes, insulin, and glycocalyx leads to excessive free radical production and inflammation, increasing susceptibility to chronic conditions like vascular disease. Maintaining optimal metabolic health and using tools like Nutrisense can help mitigate these risks.

      As we age, our bodies produce excess free radicals due to the overexpression of NOx enzymes and the decline of the glycocalyx, leading to inflammation in the vasculature. This inflammation can make the body more susceptible to chronic conditions, including vascular disease. The NOx enzymes are unique in their pro-oxidative nature, responsible for making free radicals to dilate the vasculature and facilitate glucose transport. However, as we age, the balance between NOx and insulin shifts, leading to excessive free radical production and inflammation. The glycocalyx, a mechanical sensor and tension sensor in the vasculature, can also be compromised, leading to leaky vessels and the release of immune cells that contribute to vascular damage. Understanding this complex interplay between NOx enzymes, insulin, and the glycocalyx can help us appreciate the importance of maintaining optimal metabolic health, especially as we age. Tools like the Nutrisense Continuous Glucose Monitor program can help us make better lifestyle choices and avoid chronic conditions. Additionally, electrolyte supplementation is crucial for low-carb dieters to maintain optimal health.

    • Maintaining Proper Electrolyte Balance for Optimal HealthProper electrolyte balance is essential for nerve impulses, hormonal regulation, nutrient absorption, and fluid balance. Consuming adequate electrolytes can enhance gym performance and recovery. A balanced diet, including electrolytes and carbohydrates, contributes to long-term health and wellness.

      Electrolytes play a crucial role in various bodily functions, including nerve impulses, hormonal regulation, nutrient absorption, and fluid balance. A deficiency in electrolytes can lead to common issues like headaches, muscle cramps, fatigue, and sleeplessness. Consuming adequate electrolytes can enhance gym performance and recovery. Element is a recommended electrolyte drink mix that offers a science-backed electrolyte ratio without any unnecessary additives. Additionally, the speaker shared her personal experience with electrolytes and low-carb diets. She mentioned that she faced severe gastrointestinal issues and turned to a high-beef, high-coconut oil, and low-carb diet for a reset. However, she stayed on this diet for too long and experienced weight gain and other health issues as she approached middle age. She discovered that microdosing GLP-1 agonists and reintroducing carbohydrates into her diet helped her manage her weight and improve her overall health. In essence, maintaining proper electrolyte balance is essential for optimal health, and a balanced diet, including electrolytes and carbohydrates, can contribute to long-term health and wellness.

    • Our bodies protect us from weight lossThe body increases synapses related to food intake after weight loss, overriding neurons that suppress food intake and leading to weight regain

      Our bodies have evolved to protect us from famine and weight loss, and as a result, there is a rebound effect after fat loss where the body works to regain the weight. This is due to various mechanisms, one of which is synaptic amplification, where the number of synapses in the brain related to food intake triples post-fat loss. This means that neurons that suppress food intake are overridden by neurons that make us eat more, leading to weight regain. This is an important concept to understand, as it's not typically discussed in the fitness industry but is a documented phenomenon in scientific research. Our bodies are designed to protect us, and weight loss is just one of many ways they do so. It's essential to be aware of this rebound effect and take steps to mitigate it, such as focusing on sustainable weight loss and addressing underlying hormonal imbalances.

    • Understanding weight loss beyond the scaleWeight loss involves complex body mechanisms that make maintaining it a challenge, including hormonal changes and increased hunger signals, emphasizing the importance of long-term strategies to beat the rebound effect

      Weight loss is not just about the number on the scale. The body has complex mechanisms to compensate for calorie deficits, including tripling the neural inputs that trigger the urge to eat. This is known as compensation and is a major reason why chronic weight cycling is common. The rebound effect, where weight is regained, is particularly challenging to overcome. Hormones like ghrelin and leptin play a role in this process, with ghrelin increasing and leptin decreasing after weight loss, making it harder to maintain weight loss over time. This new understanding of weight loss requires a focus on beating the rebound effect rather than just losing weight initially. The success rate of maintaining weight loss is low, and it's important to recognize that weight loss is a complex process that goes beyond just eating less and moving more.

    • Addressing hormonal imbalances post-fat lossFocus on suppressing ghrelin and elevating leptin through food choices and lifestyle modifications to improve sleep quality, reduce insulin resistance, and maintain a healthy weight as we age.

      Post-fat loss, the disrupted ratios of leptin to ghrelin can be a major obstacle. Leptin, which is responsible for longer-term appetite suppression, should ideally be higher, while ghrelin, which increases before meals and decreases afterwards, needs to be kept in check. These hormones also impact sleep quality, creating a cycle where poor sleep leads to insulin resistance and other health issues. To improve overall health, it's essential to focus on suppressing ghrelin and elevating leptin through targeted food choices and other lifestyle modifications. By addressing these hormonal imbalances, we can improve sleep quality, reduce insulin resistance, and make it easier to maintain a healthy weight as we age. It's crucial to recognize that weight loss isn't just about calories in vs. calories out, and that addressing these underlying hormonal issues can make all the difference.

    • Boosting insulin sensitivity with peptides for weight lossPeptides can aid weight loss by increasing insulin sensitivity, but should be used strategically and cycled to avoid side effects. Food impacts sleep, with certain carbs promoting onset, but long-term reliance on these foods may not be optimal.

      Insulin sensitivity boosters like peptides can be effective tools for weight loss, but they should be used strategically and cycled to avoid potential long-term side effects. The goal should be to eventually wean off these medications. Additionally, the discussion highlighted the importance of food in overall health, particularly when it comes to sleep. Food and feeding cycles impact sleep quality and onset, and certain types of carbs, when combined with other foods, can help promote sleep. This is an often overlooked aspect of the diet landscape. The body's sleep clocking mechanisms are not just driven by light and dark cycles, but also by feeding cycles. Foods that promote sleep onset, such as certain types of carbs, can be useful in helping people wind down and get to sleep, especially for those with stressful jobs. However, it's important to note that while this can be helpful in the short term, long-term reliance on these foods for sleep may not be ideal.

    • Meal choices and timing impact sleep qualitySelecting meals with carbs and protein at breakfast, avoiding high ghrelin levels, consuming sleep-promoting foods like cheese and dairy with nutmeg, and strategically timing meals can all improve sleep quality.

      The types of foods and meal patterns we consume can significantly impact our sleep quality. For instance, large meals with carbohydrates and a decent amount of protein at breakfast can advance the sleep clock and improve sleep. Conversely, high levels of ghrelin, a hunger hormone, can disrupt sleep and lead to less REM sleep, more non-REM sleep, and sleep fragmentation. Some foods, like cheese and dairy, contain sleep-promoting peptides, and adding nutmeg to these meals can further enhance sleep onset. Additionally, the physical dimension of meals plays a role in sleep regulation, as the body responds to the passage of a thick bolus through the digestive tract by releasing specific hormones related to feeding. Overall, the strategic sequencing and timing of meals can optimize various parameters, including sleep.

    • Accepting the natural sequence of famine and feastingEmbracing periods of lesser preferred food consumption during scarcity stimulates commensal bacteria, amplifying longevity pathways, and protects against toxic bacteria like Fusobacteria.

      Nature has an optimized meal plan consisting of periods of famine and feasting. This natural sequence, which includes foraging for lesser preferred foods during periods of scarcity, has synergistic effects on our health. During famine, the commensal bacteria in our gut are stimulated, amplifying longevity pathways. Additionally, the consumption of oxalate-containing foods, often vilified, actually protects us from toxic bacteria like Fusobacteria. By accepting and embracing this natural meal pattern, we can optimize our health and minimize toxicity.

    • Understanding Scarcity and Ancestral Eating for a Healthy DietConsuming a diverse range of foods, including those labeled as 'villains', protects us from toxicity and supports beneficial bacteria. Focus on foraging and feasting in a primal, balanced way for longevity.

      The key to a healthy and varied diet lies in understanding the concept of scarcity and its effect on ancestral eating. Scarcity drives us to consume a diverse range of foods, which in turn protects us from toxicity. The idea of labeling certain foods as heroes or villains is misguided, as it's often the "villain" that saves us from the potential harm of our preferred "hero" food. For instance, consuming foods rich in resistant starches and phenols feeds beneficial bacteria, preventing the production of toxic metabolites from meat fermentation. This concept holds up to scrutiny and challenges many popular diets of today. Additionally, longevity can be achieved through food restriction at times, but it's important to remember that prolonged starvation can lead to health issues. Instead, focus on foraging and feasting in a primal, balanced way.

    • Living in a Post-Truth Society: The Dangers of Disconnecting from RealityIn a post-truth society, people rely heavily on authority figures and institutions for truth, leading to conflicting 'tribes' and a disconnection from reality. This disconnection can be dangerous, as truth is a fundamental survival principle.

      We are living in an era where the concept of truth is under assault, leading to confusion and the formation of extreme dietary "tribes." This issue extends beyond diet and into society at large, as we have lost a shared framework for understanding reality. As a result, people are overly reliant on authority figures and institutions to provide truth, despite their inconsistent track records. This societal disconnection from reality makes it more challenging to discern what's true in various areas of knowledge. Consequently, we see the emergence of intense, conflicting "tribes" that attack those who challenge their beliefs, creating a post-truth society. This disconnection from reality is dangerous because truth has always been a fundamental survival principle, as it connects us to reality. The consequences of embracing nonreality, whether on an individual or societal level, can ultimately lead to death. To combat this, it's crucial to critically evaluate information and seek out truth from various sources.

    • The Disconnect from Reality in Diet and Health DiscussionsPeople react defensively to truth about health and diet, leading to a disconnect from reality, abandoning shared principles, and relying on mental submission to authority figures instead of using our own senses and deduction.

      We're facing a systemic issue where truth is being attacked, leading to a disconnection from reality. This is evident in the way people react to discussions about diet and health. For instance, speaking the truth about being overweight can lead to accusations of fat shaming or weight insensitivity. This disconnect from reality is a result of abandoning shared principles and the rise of hyperpolarization and tribalization. The standard for a healthy diet used to be diverse and nutrient-dense, but now, the way to health is seen as through non-diversity and exclusion. This is a perfect example of disconnecting from reality, as our bodies function best on homeostasis, and too much of anything can disrupt this balance. The way we arrived at these beliefs is through axiomatic induction, where we accept things as true because authority figures repeat them. This is a form of mental submission, and we live in an age where individuals have leveled down into this hegemony. To counteract this, we need to return to relying on our own senses and using deduction to make sense of the world. This is the way out of the current era of diet knownage, where we've become psychologically dependent on authority figures for truth.

    • Staying grounded in reality for personal growth and societal progressEmbrace survival as the ultimate biohack, prioritize connection to reality through sense, and stay informed through resources like vpnutrition.com for a fulfilling and sustainable life.

      Our survival and connection to reality are crucial for personal growth and societal progress. Reality has a way of asserting itself, and disconnection from it can lead to complacency and eventual hardship. Sense, or the ability to discern truth and parse reality, is essential for this connection. Joel Salatin, the guest on the podcast, emphasized the importance of survival as the ultimate biohack and the role of sense in achieving it. He also shared his resources, including his website vpnutrition.com and social media accounts, for those interested in learning more. Ultimately, the message is to stay grounded in reality and prioritize our connection to it for a fulfilling and sustainable life.

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    The Dr. Tyna Show
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    The Dr. Tyna Show
    enMay 22, 2024

    EP. 150: Eating For Health | Niklas Gustafson

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    The Dr. Tyna Show
    enMay 15, 2024

    EP. 149: You Need To Take The Stairs | Quick + Dirty

    EP. 149: You Need To Take The Stairs | Quick + Dirty
    Today’s episode is all about why you need to take the stairs EVERY. SINGLE. TIME. Beyond just physical fitness, we explore how this simple choice can transform your well-being, elevate your mood, mitigate the risk of diabetes, and so much more. I’m going over all the data, discussing proper form, and addressing how stair climbing can aid in injury recovery so you can take charge of your health, one stair at a time. Ozempic Uncovered FREE 4 Part Video Series On This Episode We Cover:  1:55 - Stairs, your mood + my family 3:15 - Data overview  4:18 - Focus on your form 8:49 - 2023 Tulane University study  10:01 - 2024 American Journal of Preventive Medicine study 11:08 - 2024 presentation at the European Society of Cardiology Sponsored By:  LMNT Get 8 FREE packs with any order at drinkLMNT.com/drtyna Timeline Nutrition Go to timelinenutrition.com/DRTYNA and use code DRTYNA for 10% off Show Links:  Tulane University Study 2024 American Journal of Preventive Medicine study 2024 presentation at the European Society of Cardiology Disclaimer: Information provided in this podcast is for informational purposes only. This information is NOT intended as a substitute for the advice provided by your physician or other healthcare professional, or any information contained on or in any product. Do not use the information provided in this podcast for diagnosing or treating a health problem or disease, or prescribing medication or other treatment. Always speak with your physician or other healthcare professional before taking any medication or nutritional, herbal or other supplement, or using any treatment for a health problem. Information provided in this blog/podcast and the use of any products or services related to this podcast by you does not create a doctor-patient relationship between you and Dr. Tyna Moore. Information and statements regarding dietary supplements have not been evaluated by the Food and Drug Administration and are not intended to diagnose, treat, cure, or prevent ANY disease.
    The Dr. Tyna Show
    enMay 10, 2024

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