hormone therapy

Today, a top menopause doctor is here to give you the science and facts on menopause and hormone replacement therapy that your doctor isn’t telling you.

This episode is a must listen because you’ll learn EXACTLY what to do to feel like yourself again.

Dr. Jen Gunter, MD, is known as the internet’s best Ob/Gyn. She is a double board-certified, fellowship-trained medical doctor and a fierce advocate for women’s health. 

She says you deserve science-backed solutions, not fairytales, and she is here to bust through all menopause myths and clear through the misinformation.

You’ll learn:

- The best intervention for menopause symptoms to help you lose weight, sleep better, and stop suffering now.

- Should you or a loved one be on hormone replacement therapy (HRT)?

- Which form of HRT is best?

- Are “bioidentical hormones” better?

After today, you will know how to hack your hormones and get your mojo back. 

Bookmark this episode and share it with every single woman in your life, because it’s time to change the paradigm: you do not have to live with symptoms that can be resolved, and you do not have to suffer.

For more resources, including links to Dr. Gunter’s research, website, and social media click here for the podcast episode page. 

If you liked this research-packed episode, you’ll love our first episode about menopause with Dr. Mary Claire Haver, MD: The #1 Menopause Doctor: How to Lose Belly Fat, Sleep Better, & Stop Suffering Now.

Connect with Mel:

• Watch the episodes on YouTube
• Follow Mel on Instagram 
• The Mel Robbins Podcast Instagram
• Mel's TikTok 
• Sign up for Mel’s newsletter 
• Disclaimer

Hey podcast community, Dr. Mark here. My team and I are so excited to offer you a 7 Day Free trial of the Dr. Hyman+ subscription for Apple Podcast. For 7 days, you get access to all this and more entirely for free!  It's so easy to sign up. Just go click the Try Free button on the Doctor’s Farmacy Podcast page in Apple Podcast. 

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As 2023 draws to a close, Liz reflects on some of the podcast conversations that she feels we need to take heed of as we think about taking care of our mental and physical health in the new year...

Liz reveals the episodes you found most useful, and talks through the ways these conversations have impacted her own life too.

The episode shares highlights from Avrum Bluming on oestrogen and why it matters, Professor Jayashri Kulkarni on how hormones influence the brain, Mary Biles on medicinal cannabis and the endocannabinoid system, Chris van Tulleken on ultra-processed foods and dementia, and Dr Jason Fung on intermittent fasting for type 2 diabetes and obesity.

Links mentioned in the episode:

• Listen to Avrum Bluming on oestrogen and why it matters,
• Listen to Professor Jayashri Kulkarni on hormones and our brains
• Listen to Mary Biles on medicinal cannabis
• Listen to Chris van Tulleken on ultra-processed foods
• Listen to Dr Jason Fung on intermittent fasting
• Pre-order A Better Second Half by Liz Earle

Hosted on Acast. See acast.com/privacy for more information.

View the Show Notes Page for This Episode

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We discuss:

• Derek’s interest in weightlifting and experimentation with anabolic steroids at a young age [3:15];
• Derek’s experience acquiring steroids from underground labs and the potential long-term fertility concerns early in his bodybuilding career [12:00];
• The backstory on More Plates, More Dates and Derek’s unique ability to blend scientific knowledge with personal observation [17:00];
• Growth hormone – from extreme use-cases to the more typical – and the misconception that it’s the “elixir of life” [21:30];
• Growth hormone 101: definition, where it comes from, and the challenges of measuring it [28:45];
• Does exogenous growth hormone compromise one’s ability to make endogenous growth hormone? [40:00];
• The use of growth hormone in restoration of tissue during periods of healing [42:00];
• Growth hormone-releasing peptides to increase endogenous GH: various peptides, risks, benefits, and comparison to exogenous growth hormone [48:45];
• The role of growth hormone in building muscle and burning fat, as well as its effects on sleep and daytime lethargy [1:02:30];
• The evolution of drug use in the sport of bodybuilding [1:10:30];
• What explains the protruding abdomens on some bodybuilders and athletes? [1:20:30];
• Death of bodybuilders [1:26:00];
• The complex interplay of hormones, and the conversion of testosterone into metabolites like DHT and estrogen [1:33:45];
• Post-finasteride syndrome and how Derek successfully treated his hair loss [1:43:15];
• Testosterone replacement therapy: compelling use-cases, side effects, and optimal dosing schedules [1:57:15];
• Aromatase inhibitors to suppress estrogen, and the misconceptions around estrogen in men [2:16:00];
• Other hormones beyond testosterone for male sex hormone replacement [2:21:00];
• The history of anabolic compounds, and the differing effects of various anabolic testosterone derivatives and related drugs [2:24:30];
• Use of SARMs by bodybuilders [2:29:45];
• Anabolic steroid and testosterone regimens of professional bodybuilders and the downstream consequences [2:36:15];
• The challenge of accurate hormone testing in the presence of anabolic steroids and supplements [2:44:45];
• The use of Clomid, hCG, and enclomiphene [2:47:15];
• Concerns about fertility: comparing the use of testosterone and hCG [3:00:30];
• The use of BPC-157 peptide for healing injuries [3:12:00]; and
• More.

Connect With Peter on Twitter, Instagram, Facebook and YouTube

Want to know more about the connection between your brain and your hormones? Professor Jayashri Kulkarni joins Liz on this episode of the podcast to share how hormones influence our brains - and what it means for longevity.

Jayashri, a professor in psychiatry, reveals what brought her to the profession, plus discusses the different types of oestrogen and their receptors, the benefits of testosterone, and the effects of other hormones on the brain.

Liz and Jayashri also cover cognitive decline, how early life trauma may impact brain biology, and how damage to the brain may be able to be repaired.

Jayashri shares how she helps to treat patients with mental health issues, and how to approach your doctor if you too are struggling.

Links mentioned in the episode:

• Follow Professor Jayashri Kulkarni on Instagram
• Learn more about Dr Louise Newson
• Listen to our episode on oestrogen with Avrum Bluming
• Listen to our episode on testosterone patches with Dr Sarah Hillman
• Listen to our episode on EMDR therapy for trauma
• Subscribe to Liz Earle Wellbeing Magazine

Hosted on Acast. See acast.com/privacy for more information.

Some of the worst symptoms of menopause — including hot flashes, sleeplessness and pain during sex — have an established treatment. Why aren’t more women offered it?

Susan Dominus, a writer for The New York Times Magazine, explains how menopause has been misunderstood both by doctors and society for years, and tells us what happened when her article about it went viral.

Guest: Susan Dominus is a writer for The New York Times Magazine.

Background reading: 

• From The New York Times Magazine: Women have been misled about menopause.
• A selection of seven books to guide you through menopause.

For more information on today’s episode, visit nytimes.com/thedaily. Transcripts of each episode will be made available by the next workday.

** All details of how to sign up for my brand-new, groundbreaking ADHD Women's Wellbeing Hormone Series are now on my website**

I've created this exclusive solo episode sharing my personal experience of navigating challenging hormones for most of my adult life and now being able to understand this better through the lens of my ADHD diagnosis.

Have a listen to this short episode and see what resonates for you and how your hormone, energy, and health challenges have shown up. I will be launching my ADHD Women's Wellbeing Hormone Series to my mailing list on the 13th of July, with special early bird pricing and offering a VIP live workshop. Sign up here for all the information.

Through the ADHD Women's Wellbeing Hormone Series want to:

• Empower you with more knowledge and awareness
• Help you Advocate for yourself
• Educate you and your loved ones about how to help yourself thrive and feel well
• Offer you medical, holistic, mindset and lifestyle tools to improve your life after an ADHD diagnosis
• Boost your confidence to know what's right for you and to trust in yourself to ask for what you deserve
• Make private medical and holistic healthcare accessible to all

Head to my website for more support, resources and information.

The New York Times accidentally admits that Michael was right in his CPAC speech, Trump gets great news in Pennsylvania, and Joe Biden mumbles incoherently. 

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How conscious are you of your bone health? Dr Kuki Avery and Dr Laura Flexer join Liz on this episode of The Liz Earle Wellbeing Show to chat more about the connections between oestrogen and bone density.

Laura and Kuki - both GPs and menopause specialists - share shocking statistics on fractures, and offer helpful advice on what we should be doing now to protect our bone health for later life. 

They cover how to tell if you’re getting enough calcium with a simple online tool, plus the importance of vitamin D for bone health.

Trigger warning: the episode also contains discussion of disordered eating and the links to poor bone health as a result.

Links mentioned in the episode:

• Learn more about Chelvey Menopause clinic
• Read report on bone health and anorexia 
• Use the Edinburgh Calcium Calculator 
• Listen to What is oestrogen and why it matters, with Avrum Bluming
• Listen to Psilocybin therapy for mental health, with Dr Ekaterina Malievskaia

Hosted on Acast. See acast.com/privacy for more information.

Menopause is a time of significant hormonal changes which can lead to a range of symptoms that can severely impact quality of life for many women. So, a drug that promises to reduce these symptoms is incredibly welcome, but it has been steeped in controversy.

HRT (Hormone replacement therapy) has been widely debated, with conflicting information about its effectiveness, with some suggesting HRT is outright dangerous. In fact, a massive study twenty years ago linked it to an increased risk of breast cancer.  As a result, the numbers of women taking HRT plummeted. So should HRT be avoided at all costs? 

In today’s episode, Jonathan is joined by the author of that very study and esteemed Professor JoAnn Manson, alongside Dr. Sarah Berry to explore the science behind HRT.

• Professor JoAnn Manson is a professor of epidemiology at the Harvard School of Public Health and one of the world's most experts on HRT and menopause having run multiple enormous studies to uncover the effects of hormone replacement therapy on women’s health.

With the help of ZOE regular Dr. Sarah Berry, they delve into the science behind HRT, empowering listeners to make informed decisions about treatment for symptoms of the menopause.

Download our FREE guide — Top 10 Tips to Live Healthier: https://zoe.com/freeguide

Timecodes:

00:00 Introduction

00:12 Jonathan's introduction

01:33 Quick Fire Questions

03:27 What is the menopause?

04:10 What is the perimenopause?

05:46 What is the state of the current conversation on the menopause?

07:13 Should women seek help about the menopause?

07:58 Why do some women have symptoms and others not?

09:15 Yougov and ZOE study results on the menopause

11:35 Why is the menopause getting more attention now?

13:39 Should we be taking these symptoms seriously?

17:10 What else can be done asides from HRT?

18:49 Studies on the relationship between diet and menopause symptoms

19:35 What can help alleviate symptoms?

21:23 Are there any specific foods that can help improve symptoms?

23:37 Are menopause specific supplements effective?

24:50 How does HRT work?

26:26 Is HRT just oestrogen?

30:59 Does testosterone have a use for menopause?

31:58 What is the controversy behind HRT?

35:56 What's the latest advice and health risks?

38:11 When should you stop hormone therapy?

40:43 Do symptoms persist when you come off of hormone therapy?

42:00 How long does HRT take to start working?

43:07 How does HRT affect weight management?

45:15 Summary

48:04 Goodbyes

48:25 Outro

Check the trials mentioned in today’s episode: 

MsFlash: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4731298/

ZOE Menopause Study: https://joinzoe.com/learn/menopause-metabolism-study

PEPI Trial: https://pubmed.ncbi.nlm.nih.gov/7807658/

Follow Sarah: https://twitter.com/saraheeberry

Follow ZOE on Instagram: <a...

Did you know that you can be perimenopausal or menopausal at any age? On this episode of The Liz Earle Wellbeing Show, Liz is joined by GP and menopause specialist Dr Louise Newson to learn more about the reasons why some women may experience non-typical onset menopause and early menopause.

Liz and Louise discuss two listeners’ questions on experiencing non-typical menopause onset due to breast cancer and Sheehan’s Syndrome, a rare condition involving injury to your pituitary gland during childbirth.

The episode delves into breast cancer and risk factors, the importance of joint decision making between doctor and patient, and the differences between HRT and contraception prescribing.

Links mentioned in the episode:

• Visit the Dr Louise Newson website
• Learn more about The Menopause Charity
• Find out more about The Balance app and website
• Purchase Dr Louise's book, The Definitive Guide to Perimenopause and Menopause
• Listen to Dr Louise's podcast
• Subscribe to Liz Earle Wellbeing Magazine

Hosted on Acast. See acast.com/privacy for more information.

Bone density for women can plummet around the time of the perimenopause and menopause.

An estimated one in two women over 50 (and who do not take HRT) worldwide will develop osteoporosis. This puts women at high risk of bone fractures, which can have a major impact on health and wellbeing.

Here Chicago-based Dr Kristi DeSapri, who specialises in bone health, joins Dr Louise Newson to talk about what can increase the risk of your bones becoming weak, the role of hormonal changes in this and what to do about it.

Hear what the latest research says about the valuable role that HRT can play in protecting bones to keep you fit and strong in the future.

Dr DeSapri shares her top three tips for listeners worried about their bone health:

1. Find out how healthy your bones are and whether you could be at risk of fractures.  This could include booking a bone density scan, or completing free online assessments and taking that information to your doctor
2. Increasing evidence suggests HRT can help protect bone health, so consider this treatment option to keep your bones strong
3. Find out about the importance of bone health so that you can be your own advocate - make sure you have the right information to make the right decisions.

You can follow Dr DeSapri on Instagram @boneandbodywh. Her website is www.boneandbodywh.com

Menopausal hormone therapy was once the most commonly prescribed treatment in the United States. In the late 1990s, some 15 million women a year were receiving a prescription for it. But in 2002, a single study, its design imperfect, found links between hormone therapy and elevated health risks for women of all ages. Panic set in; in one year, the number of prescriptions plummeted.

Hormone therapy carries risks, to be sure, as do many medications that people take to relieve serious discomfort, but dozens of studies since 2002 have provided reassurance that for healthy women under 60 whose hot flashes are troubling them, the benefits of taking hormones outweigh the risks. The treatment’s reputation, however, has never fully recovered, and the consequences have been wide-reaching.

About 85 percent of women experience menopausal symptoms. Rebecca Thurston, a professor of psychiatry at the University of Pittsburgh who studies menopause, believes that, in general, menopausal women have been underserved — an oversight that she considers one of the great blind spots of medicine.

“It suggests that we have a high cultural tolerance for women’s suffering,” Thurston said. “It’s not regarded as important.”

To hear more stories from publications like The New York Times, download Audm for iPhone or Android.

In recent years, there has been a sharp increase in the number of younger Americans who identify as transgender and are seeking medical intervention to support their transition. 

This increase has coincided with laws introduced in Republican State Houses across the country that seek to block trans youth from accessing gender-affirming care. Nowhere is the political battle more polarized and heated than in Texas. 

In the first of two episodes on the situation in Texas, we explore the story of one family seeking such care for their son when the political storm hit. 

Guest: Azeen Ghorayshi, a reporter covering the intersection between sex, gender and science for The New York Times. 

Want more from The Daily? For one big idea on the news each week from our team, subscribe to our newsletter. 

Background reading: 

• A Texas clinic for transgender adolescents closed last year amid political pressure. Its demise is evidence of how treating trans minors has become a contentious issue in Republican-controlled states.
• Texas officials have begun investigating parents of transgender adolescents for possible child abuse, according to a recent lawsuit. 

For more information on today’s episode, visit nytimes.com/thedaily. Transcripts of each episode will be made available by the next workday. 

There's a condition that leads to an increased risk of heart disease, dementia, and early death that's been affecting people for as long as they've existed. The many symptoms can severely impact quality of life - ranging from headaches and memory problems to anxiety and weight gain. 

This condition affects more than half of the world's population, but unbelievably its rarely discussed and the scientific research that exists on it is limited. 

It's called menopause, and it affects 1.2 billion women worldwide. It's not a disease, but the effects can be just as serious for some women.

Jonathan talks to the British doctor who's working to educate us about menopause and bring the discussion on the topic into the mainstream.

Dr Louise Newson is a GP, menopause specialist and founder of the Newson Health Menopause & Wellbeing Center. Director of the Balance Menopause App and the non-profit Newson Health Research and Education. Founder of The Menopause Charity.

Download our FREE guide — Top 10 Tips to Live Healthier: https://zoe.com/freeguide

Timecodes:

00:00 - Intro

00:09 - Jonathan Intro

01:11 - Episode start

01:24 - What is menopause and why is it important for Dr Louise

04:17 - Being hormone-deficient is bleak

07:27 - The overall scale of menopause

12:41 - What is HRT?

17:24 - How little menopause is talked about

19:30 - Dr Louise’s push for menopause understanding & education

23:02 -What’s the accurate test for perimenopause?

28:10 - Understanding hormone deficiency symptoms

31:58 - What else can you do besides HRT: Nutrition considerations

41:09 - Does your body shape change while menopausal?

41:55 - Summary

44:06 - Goodbyes

44:31 - Outro

Episode transcripts can be found here.

Dr Louise’s non-profit organisation about improving and understanding women’s hormone health: https://www.nhmenopausesociety.org

Check Dr Louise’s app on perimenopause and menopause: https://www.balance-menopause.com

Follow Louise: https://twitter.com/drlouisenewson

Follow ZOE on Instagram: https://www.instagram.com/zoe/

This podcast was produced by Fascinate Productions.